Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26119235 | 0.87 | EPHX2 (0.36) | EPHX2PDE4D | |
| SCHEMBL26124463 | 0.79 | PDK2 (0.37) | EPHX2HTR2AHTR2CHTR2BPDE4D | |
| SCHEMBL30546420 | 0.79 | PDK2 (0.37) | EPHX2HTR2AHTR2CHTR2BPDE4D | |
| SCHEMBL26121941 | 0.79 | EPHX2 (0.34) | EPHX2HTR2AHTR2CHTR2B | |
| SCHEMBL26125656 | 0.78 | NOTUM (0.31) | — | |
| SCHEMBL26124098 | 0.76 | PDK2 (0.36) | — | |
| SCHEMBL26124586 | 0.71 | CYP19A1 (0.34) | — | |
| SCHEMBL30546440 | 0.69 | KDM4E (0.39) | EPHX2PDE4D | |
| SCHEMBL26122721 | 0.69 | KDM4E (0.39) | EPHX2PDE4D | |
| SCHEMBL26571448 | 0.64 | GRM2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |