Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 10/20 | 0.55 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26564640 | 0.90 | PDK2 (0.54) | PDK2GAAKMT2AHSD17B10 | |
| SCHEMBL26573428 | 0.87 | PDK2 (0.52) | PDK2GAA | |
| SCHEMBL30571717 | 0.81 | PTPRC (0.59) | PDK2 | |
| SCHEMBL26116640 | 0.81 | PTPRC (0.59) | PDK2 | |
| SCHEMBL26560867 | 0.80 | PDK2 (0.58) | PDK2GAAKMT2AHSD17B10 | |
| SCHEMBL26581011 | 0.80 | PDK2 (0.54) | PDK2 | |
| SCHEMBL15090069 | 0.78 | PTPRC (0.62) | NAMPTGAAKMT2AHSD17B10 | |
| SCHEMBL15087829 | 0.78 | PTPRC (0.62) | NAMPTGAAKMT2AHSD17B10 | |
| SCHEMBL25366307 | 0.74 | PDK2 (0.72) | PDK2 | |
| SCHEMBL29523423 | 0.74 | PDK2 (0.72) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |