SCHEMBL26588486

SCHEMBL26588486

CC1(C)c2ccccc2-c2ccc(N(c3ccc4oc5ccccc5c4c3)c3ccc4oc5cc(-c6ccccc6)c6ccccc6c5c4c3)cc21

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
WEE1 P30291 1/20 0.34
ALK Q9UM73 1/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PGR P06401 1/20 0.31
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26588493 0.97 WEE1 (0.35) WEE1MAPT
SCHEMBL26588485 0.96 WEE1 (0.33) WEE1MAPTMEN1KMT2APGR
SCHEMBL26588334 0.95 WEE1 (0.34) WEE1MAPT
SCHEMBL26588600 0.94 WEE1 (0.34) WEE1MAPT
SCHEMBL26588494 0.94 WEE1 (0.34) WEE1MAPT
SCHEMBL26589232 0.94 WEE1 (0.34) WEE1MAPT
SCHEMBL26588479 0.94 WEE1 (0.34) WEE1MAPT
SCHEMBL26589110 0.94 WEE1 (0.34) WEE1MAPT
SCHEMBL24969181 0.93 ALK (0.32) WEE1ALKMAPTKDM4EMEN1
SCHEMBL26588480 0.92 WEE1 (0.33) WEE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023191353-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION COMPRISING SAME FOR FORMING ORGANIC LAYER 엘티소재주식회사 2023-10-05 WO disclosed