Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26590804 | 0.90 | PRKDC (0.53) | PRKDCATM | |
| SCHEMBL26130673 | 0.89 | PRKDC (0.56) | PRKDCATM | |
| SCHEMBL29969735 | 0.89 | PRKDC (0.56) | PRKDCATM | |
| SCHEMBL21512997 | 0.88 | PRKDC (0.65) | PRKDCATM | |
| SCHEMBL26129958 | 0.87 | PRKDC (0.59) | PRKDCATM | |
| SCHEMBL29968330 | 0.86 | PRKDC (0.57) | PRKDCATM | |
| SCHEMBL21513447 | 0.86 | PRKDC (0.57) | PRKDCATM | |
| Formic Acid SCHEMBL29970588 | 0.84 | PRKDC (0.61) | PRKDCATM | |
| Formic Acid SCHEMBL26131024 | 0.84 | PRKDC (0.61) | PRKDCATM | |
| SCHEMBL29968075 | 0.82 | PRKDC (0.56) | PRKDCATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327877-A2 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRad Therapeutics, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| EP-3784671-B1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRAD THERAPEUTICS INC (US) | 2023-10-11 | — | — | EP | disclosed |