Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147116 | 1.00 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL2898463 | 0.90 | GCK (0.46) | GCKKCNH2 | |
| SCHEMBL1146538 | 0.89 | GCK (0.59) | GCKKCNH2 | |
| SCHEMBL1427182 | 0.88 | GCK (0.46) | GCKKCNH2 | |
| SCHEMBL1146833 | 0.88 | GCK (0.54) | GCK | |
| SCHEMBL1147264 | 0.85 | GCK (0.70) | GCKKCNH2 | |
| SCHEMBL2660874 | 0.84 | GCK (0.74) | GCKKCNH2 | |
| SCHEMBL2902035 | 0.84 | GCK (0.74) | GCKKCNH2 | |
| SCHEMBL1146806 | 0.84 | GCK (0.74) | GCKKCNH2 | |
| SCHEMBL1146779 | 0.84 | GCK (0.56) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048137-A1 | Benzamide derivatives and their use as glucokinase activating agents. | AstraZeneca AB (SE) | 2009-04-15 | — | — | EP | disclosed |
| EP-1891058-A1 | HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006125972-A1 | HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |