Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 10/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30670269 | 1.00 | AVPR1A (0.49) | AVPR1AOPRD1OPRM1KCNH2OPRL1 | |
| SCHEMBL30670255 | 0.90 | AVPR1A (0.44) | AVPR1AOPRD1OPRM1KCNH2 | |
| SCHEMBL30447969 | 0.85 | AVPR1A (0.50) | AVPR1AOPRD1OPRM1KCNH2 | |
| SCHEMBL1588637 | 0.82 | AVPR1A (0.48) | AVPR1AOPRD1OPRM1KCNH2 | |
| SCHEMBL26599222 | 0.81 | AVPR1A (0.43) | AVPR1AOPRD1OPRM1KCNH2 | |
| SCHEMBL30670266 | 0.81 | AVPR1A (0.43) | AVPR1AOPRD1OPRM1KCNH2 | |
| SCHEMBL30448121 | 0.81 | AVPR1A (0.53) | AVPR1AOPRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL2519782 | 0.81 | AVPR1A (0.47) | AVPR1AOPRD1OPRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL16836155 | 0.81 | AVPR1A (0.47) | AVPR1AOPRD1OPRM1KCNH2 | |
| SCHEMBL31415638 | 0.78 | AVPR1A (0.44) | AVPR1AOPRD1OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339977-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339977-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | TYK2, JAK1, JAK3 | AVPR1A 1934/4885OPRD1 757/4885OPRM1 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.