Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30670230 | 1.00 | KMT2A (0.37) | KMT2AMEN1L3MBTL1PDE10ANPC1 | |
| SCHEMBL24251561 | 0.91 | PDE2A (0.37) | KMT2AMEN1L3MBTL1PDE10ANPC1 | |
| SCHEMBL30670274 | 0.91 | PDE2A (0.37) | KMT2AMEN1L3MBTL1PDE10ANPC1 | |
| SCHEMBL30670248 | 0.82 | PDE2A (0.39) | KMT2AMEN1L3MBTL1PDE10ANPC1 | |
| SCHEMBL26599210 | 0.82 | PDE2A (0.39) | KMT2AMEN1L3MBTL1PDE10ANPC1 | |
| SCHEMBL30558736 | 0.80 | PDE2A (0.36) | PDE10APDE2AADAMTS4MMP2MMP13 | |
| SCHEMBL25263069 | 0.80 | PDE2A (0.36) | PDE10APDE2AADAMTS4MMP2MMP13 | |
| SCHEMBL1587985 | 0.76 | MEN1 (0.40) | KMT2AMEN1LMNASMN1; SMN2OPRL1 | |
| SCHEMBL2515120 | 0.74 | OPRL1 (0.56) | KMT2AKDM4ELMNAGAAOPRL1 | |
| SCHEMBL12701930 | 0.69 | POLB (0.48) | MMP2MMP13OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339977-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2023-10-26 | — | — | US | disclosed |
| US-20230339977-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2023-10-26 | — | — | US | disclosed |
| CN-114075221-A | Substituted heteroaryl compounds, compositions and uses thereof | 广东东阳光药业有限公司 | 2022-02-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339977-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | TYK2, JAK1, JAK3 | KMT2A 732/4885MEN1 3940/4885L3MBTL1 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.