Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435890 | 0.88 | CYP3A4 (0.48) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL9435882 | 0.80 | CYP3A4 (0.38) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL15519303 | 0.77 | CYP3A4 (0.40) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL8650930 | 0.74 | — | — | |
| SCHEMBL14719798 | 0.74 | — | — | |
| SCHEMBL6429741 | 0.74 | — | — | |
| SCHEMBL15519306 | 0.74 | CYP3A4 (0.37) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL3257965 | 0.73 | CYP3A4 (0.39) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL9929 | 0.72 | — | — | |
| SCHEMBL16360618 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290519-A | Cardiovascular disorders | DIAGNOSTIC MARKERS, INC. (US) | 1994-03-01 | — | — | US | claimed |
| US-5227307-A | Binding metals to thiol groups of tissue proteins | DIAGNOSTIC MARKERS, INC. (US) | 1993-07-13 | — | — | US | claimed |
| US-4219605-A | Process for flameproofing synthetic fibre material and product | CIBA-GEIGY CORPORATION (US) | 1980-08-26 | — | — | US | claimed |
| EP-1349856-B1 | ISOINDOLIN-1-ONE GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2005-06-15 | — | — | EP | disclosed |
| US-6869453-B1 | Reactive dye compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-03-22 | — | — | US | disclosed |
| US-6723834-B1 | NITROGEN-CONTAINING HETEROCYCLE IS SUBSTITUTED WITH A HYDRATED FROM OF A REDUCING SUGAR SUCH AS SUCROSE AND GLUCOSE; IMPROVED DYE-BATH EXHAUSTION AND DYE-FIBER COVALENT FIXATION; CELLULOSIC, KERATIN, HAIR, WOOL AND SILK | NORTH CAROLINA STATE UNIVERSITY | 2004-04-20 | — | — | US | disclosed |
| US-6716969-B1 | Reactive dye compounds | NORTH CAROLINA STATE UNIVERSITY | 2004-04-06 | — | — | US | disclosed |
| US-6713613-B1 | Reactive dye compounds | NORTH CAROLINA STATE UNIVERSITY | 2004-03-30 | — | — | US | disclosed |
| EP-1179033-B1 | REACTIVE DYE COMPOUNDS | UNIV NORTH CAROLINA STATE (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1349856-A2 | ISOINDOLIN-1-ONE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-08 | — | — | EP | disclosed |
| EP-1066345-B1 | REACTIVE DYE COMPOUNDS | PROCTER & GAMBLE (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2000069973-A1 | REACTIVE DYE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000069974-A1 | REACTIVE DYE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-1999051686-A1 | REACTIVE DYE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |
| WO-1999051684-A1 | REACTIVE DYE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |
| WO-1999051683-A1 | REACTIVE DYE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |
| WO-1999051685-A1 | REACTIVE DYE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |
| EP-0080919-A1 | Lubricant composition used in a high-pressure ethylene polymerisation process | Société Chimique des Charbonnages (FR) | 1983-06-08 | — | — | EP | disclosed |
| US-4219605-A | Process for flameproofing synthetic fibre material and product | CIBA-GEIGY CORPORATION (US) | 1980-08-26 | — | — | US | disclosed |
| US-4007211-A | OXIDATIVE DECARBOXYLATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1977-02-08 | — | — | US | disclosed |