SCHEMBL2660635

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2660111	0.84	GRM4 (0.58)	GRM4FADS1PDPK1JAK2MAPK1
	SCHEMBL2667982	0.84	GRM4 (0.58)	GRM4FADS1MAPK1NPC1RAB9A
	SCHEMBL2660645	0.84	GRM4 (0.58)	GRM4FADS1MAPK1
	SCHEMBL2668091	0.82	GRM4 (0.55)	GRM4FADS1PDPK1JAK2MAPK1
	SCHEMBL2662181	0.81	GRM4 (0.54)	GRM4MAPK1RIPK2
	SCHEMBL2660583	0.81	GRM4 (0.54)	GRM4FADS1MAPK1
	SCHEMBL2662190	0.81	GRM4 (0.54)	GRM4FADS1JAK2DYRK1AAURKB
	SCHEMBL2654720	0.81	GRM4 (0.54)	GRM4FADS1MAPK1MEN1NPC1
	SCHEMBL2659835	0.81	GRM4 (0.54)	GRM4FADS1CSF1RMAPK9CLK4
	SCHEMBL2667991	0.79	GRM4 (0.52)	GRM4FADS1JAK2MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.