Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.49 |
| ▸ | SRC | P12931 | 6/20 | 0.44 |
| ▸ | ABL1 | P00519 | 5/20 | 0.44 |
| ▸ | PRKDC | P78527 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | HCK | P08631 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | MTOR | P42345 | 4/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.44 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22498197 | 0.99 | PIK3CD (0.50) | PIK3CDPIK3CGPIK3CBPIK3CASRC | |
| SCHEMBL29641606 | 0.99 | PIK3CD (0.50) | PIK3CDPIK3CGPIK3CBPIK3CASRC | |
| SCHEMBL22504983 | 0.99 | PIK3CD (0.50) | PIK3CDPIK3CGPIK3CBPIK3CASRC | |
| SCHEMBL22498067 | 0.99 | PIK3CD (0.50) | PIK3CDPIK3CGPIK3CBPIK3CASRC | |
| Hydrochloric Acid SCHEMBL22498347 | 0.98 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CASRC | |
| Hydrochloric Acid SCHEMBL29641518 | 0.98 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CASRC | |
| Bromide SCHEMBL29641497 | 0.98 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CASRC | |
| Hydrochloric Acid SCHEMBL22498242 | 0.98 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CASRC | |
| Hydrochloric Acid SCHEMBL30679710 | 0.98 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CASRC | |
| SCHEMBL22498167 | 0.96 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3CBPIK3CASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947384-B1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2023-11-01 | — | — | EP | claimed |