Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 14/20 | 0.73 |
| ▸ | IKZF1 | Q13422 | 6/20 | 0.73 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26609838 | 0.92 | IKZF2 (0.71) | IKZF2IKZF1CRBN | |
| SCHEMBL26609845 | 0.92 | IKZF2 (0.73) | IKZF2IKZF1CRBN | |
| SCHEMBL26610593 | 0.92 | IKZF2 (0.71) | IKZF2IKZF1CRBN | |
| SCHEMBL29663817 | 0.90 | IKZF2 (0.84) | IKZF2IKZF1CRBN | |
| SCHEMBL22345817 | 0.90 | IKZF2 (0.84) | IKZF2IKZF1CRBN | |
| SCHEMBL26609909 | 0.89 | IKZF2 (0.68) | IKZF2IKZF1CRBN | |
| SCHEMBL26610073 | 0.89 | IKZF2 (0.68) | IKZF2IKZF1CRBN | |
| SCHEMBL26610215 | 0.89 | IKZF2 (0.68) | IKZF2IKZF1CRBN | |
| SCHEMBL26610067 | 0.89 | IKZF2 (0.68) | IKZF2IKZF1CRBN | |
| SCHEMBL26609166 | 0.89 | IKZF2 (0.68) | IKZF2IKZF1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | disclosed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | disclosed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | CSNK1A1, CSNK1D, CSNK1G1 | IKZF2 2228/4885IKZF1 2053/4885CRBN 2723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.