Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 14/20 | 0.75 |
| ▸ | EGFR | P00533 | 2/20 | 0.74 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.62 |
| ▸ | FLT4 | P35916 | 1/20 | 0.62 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.56 |
| ▸ | ULK1 | O75385 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16752965 | 0.87 | ALK (1.00) | ALKEGFRULK1 | |
| SCHEMBL26611783 | 0.87 | EGFR (0.74) | ALKEGFRPTK2FLT4 | |
| SCHEMBL29832366 | 0.85 | EGFR (1.00) | ALKEGFR | |
| SCHEMBL21846968 | 0.85 | EGFR (1.00) | ALKEGFR | |
| SCHEMBL26612055 | 0.83 | EGFR (0.75) | ALKEGFRPTK2FLT4 | |
| SCHEMBL26611925 | 0.82 | EGFR (0.75) | ALKEGFRPTK2FLT4 | |
| SCHEMBL26611961 | 0.81 | EGFR (0.72) | ALKEGFRPTK2FLT4 | |
| SCHEMBL16752944 | 0.81 | ALK (1.00) | ALK | |
| SCHEMBL16752967 | 0.81 | ALK (1.00) | ALK | |
| SCHEMBL26611761 | 0.80 | EGFR (0.73) | ALKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640246-B1 | N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2023-11-01 | — | — | EP | claimed |