Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 7/20 | 0.58 |
| ▸ | MERTK | Q12866 | 14/20 | 0.56 |
| ▸ | AXL | P30530 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626118 | 0.89 | MERTK (0.69) | TYRO3MERTKAXL | |
| SCHEMBL29626217 | 0.89 | TYRO3 (0.68) | TYRO3MERTKAXL | |
| SCHEMBL29626161 | 0.87 | MERTK (0.69) | TYRO3MERTKAXL | |
| SCHEMBL29626143 | 0.86 | MERTK (0.67) | TYRO3MERTKAXL | |
| SCHEMBL29626211 | 0.86 | MERTK (0.54) | TYRO3MERTKAXL | |
| SCHEMBL29626135 | 0.83 | TYRO3 (0.65) | TYRO3MERTKAXL | |
| SCHEMBL29626182 | 0.82 | MERTK (0.69) | TYRO3MERTKAXL | |
| SCHEMBL19377786 | 0.81 | TYRO3 (0.86) | TYRO3MERTKAXL | |
| SCHEMBL29626216 | 0.81 | MERTK (0.66) | TYRO3MERTKAXL | |
| SCHEMBL29626188 | 0.81 | MERTK (0.72) | TYRO3MERTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436461-B1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORP (US) | 2023-11-01 | — | — | EP | claimed |
| CN-114456175-B | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-114456176-B | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-114456175-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114456176-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |