Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 13/20 | 1.00 |
| ▸ | MERTK | Q12866 | 11/20 | 1.00 |
| ▸ | TYRO3 | Q06418 | 10/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377852 | 1.00 | AXL (1.00) | AXLMERTKTYRO3 | |
| SCHEMBL26613622 | 0.90 | AXL (0.81) | AXLMERTKTYRO3 | |
| SCHEMBL19377728 | 0.90 | AXL (0.81) | AXLMERTKTYRO3 | |
| SCHEMBL26613621 | 0.88 | AXL (0.79) | AXLMERTKTYRO3 | |
| SCHEMBL19377714 | 0.88 | AXL (0.79) | AXLMERTKTYRO3 | |
| SCHEMBL19377745 | 0.85 | AXL (0.73) | AXLMERTKTYRO3 | |
| SCHEMBL19377664 | 0.84 | AXL (0.72) | AXLMERTKTYRO3 | |
| SCHEMBL29626293 | 0.82 | AXL (0.69) | AXLMERTKTYRO3 | |
| SCHEMBL20335585 | 0.78 | AXL (0.63) | AXLMERTK | |
| SCHEMBL16709457 | 0.78 | AXL (0.63) | AXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436461-B1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORP (US) | 2023-11-01 | — | — | EP | claimed |