Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 14/20 | 0.56 |
| ▸ | AXL | P30530 | 2/20 | 0.56 |
| ▸ | TYRO3 | Q06418 | 7/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626195 | 0.87 | MERTK (0.68) | MERTKAXLTYRO3 | |
| SCHEMBL29626187 | 0.87 | MERTK (0.53) | MERTKAXLTYRO3 | |
| SCHEMBL29626135 | 0.83 | TYRO3 (0.65) | MERTKAXLTYRO3 | |
| SCHEMBL29626182 | 0.81 | MERTK (0.69) | MERTKAXLTYRO3 | |
| SCHEMBL29626143 | 0.81 | MERTK (0.67) | MERTKAXLTYRO3 | |
| SCHEMBL29626225 | 0.80 | MERTK (0.68) | MERTKAXLTYRO3 | |
| SCHEMBL19377753 | 0.80 | MERTK (0.61) | MERTKAXLTYRO3 | |
| SCHEMBL19377873 | 0.80 | MERTK (0.78) | MERTKAXLTYRO3 | |
| SCHEMBL29626248 | 0.79 | TYRO3 (0.69) | MERTKAXLTYRO3 | |
| SCHEMBL29626150 | 0.78 | MERTK (0.68) | MERTKAXLTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436461-B1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORP (US) | 2023-11-01 | — | — | EP | disclosed |