Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25393302 | 0.84 | MAPT (0.57) | MAPTSMN1; SMN2HTTRECQLCYP1A2 | |
| SCHEMBL25397269 | 0.81 | MAPT (0.53) | MAPTSMN1; SMN2HTTRECQLCYP1A2 | |
| SCHEMBL25393182 | 0.81 | MAPT (0.53) | MAPTSMN1; SMN2HTTRECQLCYP1A2 | |
| SCHEMBL15603526 | 0.80 | MAPT (0.80) | MAPTSMN1; SMN2HTTRECQLCYP1A2 | |
| SCHEMBL1456599 | 0.76 | MAPT (0.64) | MAPTSMN1; SMN2HTTRECQLCYP1A2 | |
| SCHEMBL29929233 | 0.76 | MAPT (0.64) | MAPTSMN1; SMN2HTTRECQLCYP1A2 | |
| SCHEMBL28962152 | 0.76 | MAPT (0.64) | MAPTSMN1; SMN2HTTRECQLCYP1A2 | |
| SCHEMBL30613396 | 0.75 | MAPT (0.36) | MAPTSMN1; SMN2HTTRECQLCYP1A2 | |
| SCHEMBL26719196 | 0.75 | MAPT (0.36) | MAPTSMN1; SMN2HTTRECQLCYP1A2 | |
| SCHEMBL30613397 | 0.72 | MAPT (0.65) | MAPTSMN1; SMN2HTTRECQLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211850-A1 | KCNT1 INHIBITORS COMPRISING AN ISOXAZOLE OR OXADIAZOLE CORE AND METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-11-02 | — | — | WO | disclosed |