Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044967 | 0.87 | KDM4E (0.39) | MPLEPHX2KDM4ESCN9AGRIA1 | |
| SCHEMBL1401600 | 0.78 | MPL (0.46) | MPLKCNN4TRPA1EPHX2KDM4E | |
| SCHEMBL255271 | 0.78 | EPHX2 (0.43) | MPLKCNN4EPHX2CYP2D6SLC6A2 | |
| SCHEMBL29635691 | 0.78 | EPHX2 (0.43) | MPLKCNN4EPHX2CYP2D6SLC6A2 | |
| SCHEMBL24499252 | 0.75 | MPL (0.37) | MPLKCNN4TRPA1EPHX2KDM4E | |
| SCHEMBL22686218 | 0.75 | MPL (0.37) | MPLKCNN4TRPA1EPHX2KDM4E | |
| SCHEMBL4218979 | 0.75 | ALB (0.39) | MPLKCNN4TRPA1EPHX2KDM4E | |
| SCHEMBL24886371 | 0.75 | KCNN4 (0.39) | MPLKCNN4TRPA1EPHX2KDM4E | |
| SCHEMBL2311679 | 0.75 | MPL (0.37) | MPLKCNN4TRPA1EPHX2KDM4E | |
| SCHEMBL900976 | 0.75 | MPL (0.44) | MPLTRPA1EPHX2KDM4ESYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | claimed |
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | disclosed |