Mannose 6-Phosphate

Mannose 6-Phosphate

SCHEMBL26619699

O=CC(O)C(O)C(O)C(O)CO.O=CC(O)C(O)C(O)C(O)COP(=O)(O)O

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.66
PGD P52209 3/20 0.43
PGK1 P00558 1/20 0.38
PGK2 P07205 1/20 0.38
LMNA P02545 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannose 6-Phosphate SCHEMBL6245545 1.00 MPI (0.66) MPIPGDPGK1PGK2LMNA
Mannose 6-Phosphate SCHEMBL6054950 1.00 MPI (0.66) MPIPGDPGK1PGK2LMNA
Demannose SCHEMBL27876341 0.95 MPI (0.74) MPIPGDPGK1PGK2LMNA
Xylose SCHEMBL25294613 0.95 MPI (0.68) MPIPGDPGK1PGK2LMNA
Xylose SCHEMBL1125483 0.95 MPI (0.68) MPIPGDPGK1PGK2LMNA
Mannose 6-Phosphate SCHEMBL489269 0.94 MPI (0.58) MPIPGDPGK1PGK2LMNA
Xylose SCHEMBL3257333 0.93 MPI (0.66) MPIPGDPGK1PGK2LMNA
Adonitol SCHEMBL21407015 0.93 MPI (0.66) MPIPGDPGK1PGK2LMNA
Ribitol SCHEMBL19329050 0.93 MPI (0.66) MPIPGDPGK1PGK2LMNA
Mannose 6-Phosphate SCHEMBL1874195 0.93 MPI (0.75) MPIPGDPGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109196097-B Method for selecting high M6P recombinant proteins 阿米库斯治疗学公司 2024-06-21 CN claimed
US-20230391853-A1 Antibody against Novel Coronavirus, and Reagent and Kit for Detecting Novel Coronavirus FAPON BIOTECH INC. (CN) 2023-12-07 US claimed
CN-109196097-B Method for selecting high M6P recombinant proteins 阿米库斯治疗学公司 2024-06-21 CN disclosed
CN-110430801-B Treatment of gastrointestinal disorders with TNF inhibitors 比奥拉治疗股份有限公司 2024-04-30 CN disclosed
WO-2023213978-A1 PRODUCTION OF MOLECULES BY PERIPLASMIC ENZYMATIC CATALYSIS BIOC3 (FR) 2023-11-09 WO disclosed
CN-112255219-A 1, 5-sorbitan determination kit, and preparation method and application thereof 中拓生物有限公司 2021-01-22 CN disclosed
CN-107108656-B N- substitution -3,5- disubstituted benzenes Carbox amide and its preparation method and application 中国科学院上海药物研究所 2019-11-05 CN disclosed
CN-109476749-A The adoptive T cell therapy of improvement 豪夫迈·罗氏有限公司 2019-03-15 CN disclosed
CN-108700582-A Quality of immune synapses predicts potency of Chimeric Antigen Receptor (CAR) T cells 刘东方 2018-10-23 CN disclosed