Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 7/20 | 0.55 |
| ▸ | CDC25B | P30305 | 7/20 | 0.55 |
| ▸ | CDC25C | P30307 | 6/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302635 | 0.93 | CDC25A (0.60) | CDC25ACDC25BCDC25CALOX5ALDH1A1 | |
| SCHEMBL12393814 | 0.86 | CDC25A (0.44) | CDC25ACDC25BCDC25C | |
| SCHEMBL82554 | 0.86 | CDC25A (0.69) | CDC25ACDC25BCDC25CALOX5ALDH1A1 | |
| SCHEMBL17706772 | 0.84 | CDC25A (0.72) | CDC25ACDC25BCDC25CALOX5ALDH1A1 | |
| SCHEMBL6242255 | 0.84 | CDC25A (0.72) | CDC25ACDC25BCDC25CALOX5ALDH1A1 | |
| SCHEMBL11176370 | 0.84 | CDC25A (0.72) | CDC25ACDC25BCDC25CALOX5ALDH1A1 | |
| SCHEMBL6243699 | 0.84 | CDC25A (0.72) | CDC25ACDC25BCDC25CALOX5ALDH1A1 | |
| SCHEMBL9631357 | 0.84 | CDC25A (0.72) | CDC25ACDC25BCDC25CALOX5ALDH1A1 | |
| SCHEMBL137358 | 0.83 | CDC25A (0.38) | CDC25ACDC25BCDC25CALDH1A1TDP1 | |
| SCHEMBL22654548 | 0.83 | CDC25A (0.38) | CDC25ACDC25BCDC25CALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070281942-A1 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281942-A1 | GLUCOKINASE ACTIVATORS | GCK, GCKR, HK1 | CDC25A 4506/4885CDC25B 4433/4885CDC25C 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.