SCHEMBL26622697

SCHEMBL26622697

Cc1ccc(C(=O)NC2CC2)cc1-c1ccc(C(=O)C2CCCC2)cc1

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 20/20 0.70
CYP2C9 P11712 2/20 0.64
HSPB1 P04792 1/20 0.64
MAPK11 Q15759 1/20 0.64
LCK P06239 1/20 0.57
CSF1R P07333 1/20 0.57
KDR P35968 1/20 0.57
MAP2K1 Q02750 1/20 0.55
RAF1 P04049 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C19 P33261 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26622758 0.99 MAPK14 (0.68) MAPK14CYP2C9HSPB1MAPK11LCK
SCHEMBL26622703 0.99 MAPK14 (0.68) MAPK14CYP2C9HSPB1MAPK11LCK
SCHEMBL26622702 0.97 MAPK14 (0.70) MAPK14CYP2C9HSPB1MAPK11LCK
SCHEMBL26622796 0.95 MAPK14 (0.73) MAPK14CYP2C9HSPB1MAPK11LCK
SCHEMBL5631456 0.90 MAPK14 (0.81) MAPK14CYP2C9HSPB1MAPK11LCK
SCHEMBL26622710 0.89 MAPK14 (0.68) MAPK14CYP2C9HSPB1MAPK11LCK
SCHEMBL5630096 0.88 MAPK14 (0.87) MAPK14CYP2C9HSPB1MAPK11LCK
SCHEMBL26716816 0.87 MAPK14 (0.65) MAPK14CYP2C9HSPB1MAPK11LCK
SCHEMBL30678666 0.86 MAPK14 (0.64) MAPK14CYP2C9HSPB1MAPK11LCK
SCHEMBL30678671 0.86 MAPK14 (0.64) MAPK14CYP2C9HSPB1MAPK11LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240109839-A1 NOVEL COMPOUND EXHIBITING ANTI-INFLAMMATORY ACTIVITY AS P38 MAP KINASE INHIBITOR PRAZERTHERAPEUTICS INC. (KR) 2024-04-04 US claimed
EP-4273120-A1 NOVEL COMPOUND EXHIBITING ANTI-INFLAMMATORY ACTIVITY AS P38 MAP KINASE INHIBITOR Prazertherapeutics Inc. (KR) 2023-11-08 EP claimed
US-20240109839-A1 NOVEL COMPOUND EXHIBITING ANTI-INFLAMMATORY ACTIVITY AS P38 MAP KINASE INHIBITOR PRAZERTHERAPEUTICS INC. (KR) 2024-04-04 US disclosed
CN-117136177-A Novel compounds exhibiting anti-inflammatory activity as P38MAP kinase inhibitors 普瑞泽治疗公司 2023-11-28 CN disclosed
EP-4273120-A1 NOVEL COMPOUND EXHIBITING ANTI-INFLAMMATORY ACTIVITY AS P38 MAP KINASE INHIBITOR Prazertherapeutics Inc. (KR) 2023-11-08 EP disclosed
WO-2022164041-A1 NOVEL COMPOUND EXHIBITING ANTI-INFLAMMATORY ACTIVITY AS P38 MAP KINASE INHIBITOR (주)프레이저테라퓨틱스 2022-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109839-A1 NOVEL COMPOUND EXHIBITING ANTI-INFLAMMATORY ACTIVITY AS P38 MAP KINASE INHIBITOR MAPK1, MAPKAPK2, MAPKAPK5 MAPK14 12/4885CYP2C9 4016/4885HSPB1 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.