Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 4/20 | 0.41 |
| ▸ | GCGR | P47871 | 9/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | GIPR | P48546 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662297 | 0.79 | GCGR (0.54) | GCGRSERPINE1GIPRHDAC3HDAC1 | |
| SCHEMBL2661746 | 0.72 | GCGR (0.48) | GCGRSERPINE1GIPRCYP2D6 | |
| SCHEMBL2665081 | 0.70 | GCGR (0.49) | GCGRSERPINE1GIPRCYP2D6 | |
| SCHEMBL4096042 | 0.70 | GCGR (0.49) | GCGRSERPINE1GIPREPHX2CYP2D6 | |
| SCHEMBL2659967 | 0.70 | GCGR (0.47) | GCGRSERPINE1GIPRCYP2D6 | |
| SCHEMBL2665105 | 0.70 | GCGR (0.55) | GCGRGIPRADCY6ADCY3ADCY9 | |
| SCHEMBL2650399 | 0.70 | GCGR (0.50) | GCGRSERPINE1GIPREPHX2CYP2D6 | |
| SCHEMBL2665028 | 0.70 | GCGR (0.59) | GCGRSERPINE1GIPRADCY6ADCY3 | |
| SCHEMBL2665188 | 0.70 | BCL2L1 (0.48) | GCGRGIPREPHX2CYP2D6ADCY6 | |
| SCHEMBL4096282 | 0.70 | GCGR (0.46) | GCGRSERPINE1GIPRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183229-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |