SCHEMBL26626366

SCHEMBL26626366

Clc1nc(-c2ccc(-c3ccccc3)cc2)cc(-c2cccc([Si](c3ccccc3)(c3ccccc3)c3ccccc3)c2)n1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 0.65
KMT2A Q03164 10/20 0.65
ALDH1A1 P00352 7/20 0.65
HPGD P15428 7/20 0.65
L3MBTL1 Q9Y468 3/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
MAPT P10636 6/20 0.58
KDM4E B2RXH2 6/20 0.58
TDP1 Q9NUW8 2/20 0.58
LMNA P02545 3/20 0.43
GLA P06280 2/20 0.43
CTRC Q99895 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41
NTSR1 P30989 1/20 0.41
KMO O15229 1/20 0.41
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25753198 0.88 MEN1 (0.51) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL22912145 0.84 MEN1 (0.77) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL10051514 0.84 MEN1 (0.91) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL13728744 0.84 MEN1 (0.91) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL30939448 0.84 MEN1 (0.91) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL24212278 0.84 MEN1 (0.91) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL16161050 0.84 MEN1 (0.91) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL23268241 0.84 MEN1 (0.58) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL24253130 0.83 MEN1 (0.61) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL26416883 0.83 CYP19A1 (0.49) MEN1KMT2AALDH1A1HPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023211213-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2023-11-02 WO disclosed
WO-2023211213-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2023-11-02 WO disclosed