Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.40 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.40 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.40 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.40 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2646810 | 0.89 | PRKAA2 (0.47) | ADORA3CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL2647009 | 0.85 | GAA (0.42) | ADORA3CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL2647867 | 0.80 | AR (0.41) | ADORA3KDM4EL3MBTL1HTTALDH1A1 | |
| SCHEMBL27525560 | 0.78 | GCGR (0.43) | ADORA3CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL27525559 | 0.77 | PRKAA2 (0.51) | — | |
| SCHEMBL9267251 | 0.76 | GCGR (0.53) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL2647574 | 0.74 | PRKAA2 (0.47) | — | |
| SCHEMBL2662929 | 0.73 | PRKAA2 (0.44) | KDM4EALDH1A1MAPT | |
| SCHEMBL9271191 | 0.71 | GCGR (0.60) | KDM4EL3MBTL1HTTALDH1A1POLB | |
| SCHEMBL27525530 | 0.71 | AR (0.42) | ALDH1A1SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |