Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 11/20 | 0.54 |
| ▸ | GIPR | P48546 | 8/20 | 0.54 |
| ▸ | STAT3 | P40763 | 4/20 | 0.48 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663171 | 0.90 | GCGR (0.55) | GCGRGIPRSTAT3UBE2MDCUN1D1 | |
| SCHEMBL2663327 | 0.88 | GCGR (0.52) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2663198 | 0.88 | GCGR (0.58) | GCGRGIPRSTAT3UBE2MDCUN1D1 | |
| SCHEMBL2663351 | 0.88 | GCGR (0.52) | GCGRGIPRSTAT3 | |
| SCHEMBL2663084 | 0.88 | GCGR (0.52) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2663341 | 0.88 | GCGR (0.52) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL9072918 | 0.88 | GCGR (0.67) | GCGRGIPRSTAT3UBE2MDCUN1D1 | |
| SCHEMBL2663062 | 0.88 | GCGR (0.69) | GCGRGIPRSTAT3 | |
| SCHEMBL2663151 | 0.88 | GCGR (0.53) | GCGRGIPRSTAT3HDAC3HDAC11 | |
| SCHEMBL2663089 | 0.86 | GCGR (0.51) | GCGRGIPRSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |