Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26632137 | 0.89 | MAPT (0.39) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL26632154 | 0.88 | CHRM4 (0.41) | MAPTALDH1A1LMNA | |
| SCHEMBL30628529 | 0.87 | EIF2AK4 (0.42) | MAPTALDH1A1LMNAHPGD | |
| SCHEMBL26632139 | 0.85 | CHRM4 (0.41) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL26632120 | 0.85 | MAPT (0.37) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL26632145 | 0.85 | MAPT (0.37) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL26632155 | 0.85 | MAPT (0.37) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL26632114 | 0.84 | MAPT (0.36) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL26632164 | 0.84 | CHRM4 (0.41) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL26632117 | 0.84 | MAPT (0.36) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211256-A1 | NOVEL PIM KINASE INHIBITORS AND USES THEREOF | 제일약품주식회사 | 2023-11-02 | — | — | WO | disclosed |