Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 12/20 | 0.62 |
| ▸ | STAT3 | P40763 | 5/20 | 0.51 |
| ▸ | GIPR | P48546 | 8/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651716 | 0.87 | GCGR (0.78) | GCGRSTAT3GIPRGLP1R | |
| SCHEMBL4092020 | 0.87 | GCGR (0.61) | GCGRSTAT3GIPR | |
| SCHEMBL2663310 | 0.86 | GCGR (0.61) | GCGRSTAT3GIPROPRM1OPRK1 | |
| SCHEMBL2663178 | 0.85 | GCGR (0.58) | GCGRSTAT3GIPROPRM1OPRK1 | |
| SCHEMBL4096149 | 0.84 | GCGR (0.59) | GCGRSTAT3GIPROPRM1OPRK1 | |
| SCHEMBL2663083 | 0.83 | GCGR (0.71) | GCGRSTAT3GIPRGLP1R | |
| SCHEMBL9070861 | 0.82 | GCGR (0.65) | GCGRSTAT3GIPROPRM1OPRK1 | |
| SCHEMBL6755480 | 0.82 | GCGR (0.65) | GCGRSTAT3GIPROPRM1OPRK1 | |
| SCHEMBL2653143 | 0.82 | GCGR (0.78) | GCGRSTAT3GIPRGLP1R | |
| SCHEMBL2663307 | 0.82 | GCGR (0.63) | GCGRSTAT3GIPROPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |