SCHEMBL26634653

SCHEMBL26634653

COC(=O)C(CCC(=O)NCCNC(=O)OC(C)(C)C)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 3/20 0.39
TDP1 Q9NUW8 4/20 0.37
ATM Q13315 1/20 0.36
POLB P06746 1/20 0.35
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
ALDH1A1 P00352 1/20 0.35
CA12 O43570 2/20 0.34
CA9 Q16790 2/20 0.34
EPHX1 P07099 1/20 0.34
HTT P42858 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
MALT1 Q9UDY8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24796279 1.00 MEN1 (0.41) MEN1KMT2AGAANPSR1TDP1
SCHEMBL21389234 1.00 MEN1 (0.41) MEN1KMT2AGAANPSR1TDP1
SCHEMBL21384171 0.89 MEN1 (0.48) MEN1KMT2AGAANPSR1TDP1
SCHEMBL16534098 0.89 MEN1 (0.46) MEN1KMT2AGAANPSR1TDP1
SCHEMBL26745132 0.84 MEN1 (0.46) MEN1KMT2AGAANPSR1TDP1
SCHEMBL26745078 0.84 MEN1 (0.46) MEN1KMT2AGAANPSR1TDP1
SCHEMBL28526406 0.84 TDP1 (0.50) MEN1KMT2AGAANPSR1TDP1
SCHEMBL28526408 0.84 TDP1 (0.50) MEN1KMT2AGAANPSR1TDP1
SCHEMBL15297704 0.80 SERPINE1 (0.39) MEN1KMT2AGAANPSR1TDP1
SCHEMBL31757953 0.80 SERPINE1 (0.39) MEN1KMT2AGAANPSR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 US disclosed
CN-112236161-A Modulators of G protein-coupled receptors 卡莫特治疗学股份有限公司 2021-01-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR MEN1 3167/4885KMT2A 3040/4885GAA 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.