Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17172988 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP3A4PIK3CDALDH1A1CYP2C19 | |
| SCHEMBL24317731 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP3A4PIK3CDALDH1A1CYP2C19 | |
| SCHEMBL12921202 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP3A4PIK3CDALDH1A1CYP2C19 | |
| SCHEMBL26053285 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP3A4PIK3CDALDH1A1CYP2C19 | |
| SCHEMBL25708741 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP3A4PIK3CDALDH1A1CYP2C19 | |
| SCHEMBL13892470 | 0.75 | CYP2D6 (0.37) | SMN1; SMN2CYP3A4PIK3CDALDH1A1CYP2C19 | |
| SCHEMBL26634753 | 0.75 | CYP4F2 (0.35) | SMN1; SMN2CYP3A4PIK3CDALDH1A1CYP2C19 | |
| SCHEMBL4815629 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP3A4ALDH1A1CYP2C19MAPK1 | |
| SCHEMBL4815638 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP3A4ALDH1A1CYP2C19MAPK1 | |
| SCHEMBL13819904 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP3A4PIK3CDALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | IKZF1, IKZF3, IKZF2 | SMN1; SMN2 1860/4885CYP3A4 2637/4885PIK3CD 1796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.