Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.44 |
| ▸ | GIPR | P48546 | 15/20 | 0.44 |
| ▸ | GLP1R | P43220 | 4/20 | 0.41 |
| ▸ | GCG | P01275 | 1/20 | 0.39 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072746 | 0.92 | GCGR (0.47) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2663607 | 0.92 | GCGR (0.44) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL13800821 | 0.90 | GCGR (0.43) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2663610 | 0.90 | GCGR (0.47) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2663480 | 0.89 | GCGR (0.47) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL9072814 | 0.88 | GCGR (0.47) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2663605 | 0.88 | GCGR (0.48) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL9072810 | 0.88 | GCGR (0.41) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2663524 | 0.87 | GCGR (0.48) | GCGRGIPR | |
| SCHEMBL2663477 | 0.87 | GCGR (0.51) | GCGRGIPRGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |