SCHEMBL2663585

SCHEMBL2663585

CC(C)c1nc(C(C)C)c(CO)c(-c2ccc(F)cc2)c1CN

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8949822 0.93 GCGR (0.88) GCGR
SCHEMBL2647903 0.87 GCGR (1.00) GCGR
SCHEMBL27525493 0.86 GCGR (0.70) GCGR
SCHEMBL2647390 0.84 GCGR (0.75) GCGR
SCHEMBL2647635 0.84 GCGR (1.00) GCGR
SCHEMBL27531127 0.84 GCGR (0.67) GCGR
SCHEMBL2656279 0.84 GCGR (1.00) GCGR
SCHEMBL8949777 0.84 GCGR (0.74) GCGR
SCHEMBL2648671 0.84 GCGR (0.70) GCGR
SCHEMBL2649470 0.83 GCGR (0.73) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6218431-B1 GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES BAYER CORPORATION 2001-04-17 US disclosed