Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | IL6ST | P40189 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 8/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26640265 | 1.00 | PPARA (0.51) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL25409097 | 1.00 | PPARA (0.51) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL25409093 | 1.00 | PPARA (0.51) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL25409090 | 1.00 | PPARA (0.51) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL21724414 | 0.89 | PPARA (0.52) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL21724552 | 0.89 | PPARA (0.52) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL21724550 | 0.89 | PPARA (0.52) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL21724415 | 0.89 | PPARA (0.52) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL21724412 | 0.89 | PPARA (0.52) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL13316517 | 0.89 | PPARA (0.54) | PPARAIL6STNAAAIDH1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220715-A1 | OXOINDOLINYL AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2023-11-16 | — | — | WO | disclosed |