Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643642 | 1.00 | CRBN (0.47) | CRBNDDB1POLBHTR2AHTR2C | |
| SCHEMBL26641449 | 0.82 | CRBN (0.51) | CRBNDDB1POLB | |
| SCHEMBL29013196 | 0.80 | CRBN (0.53) | CRBNDDB1POLB | |
| SCHEMBL26641500 | 0.79 | CRBN (0.39) | CRBNDDB1POLB | |
| SCHEMBL25031460 | 0.78 | CRBN (0.52) | CRBNDDB1POLB | |
| SCHEMBL30479047 | 0.78 | CRBN (0.52) | CRBNDDB1POLB | |
| SCHEMBL26641399 | 0.78 | CRBN (0.58) | CRBNDDB1POLB | |
| SCHEMBL30643638 | 0.78 | CRBN (0.58) | CRBNDDB1POLB | |
| SCHEMBL31342760 | 0.77 | CRBN (0.51) | CRBNDDB1POLB | |
| SCHEMBL26641065 | 0.75 | CRBN (0.54) | CRBNDDB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |