Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCYAP1R1 | P41586 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.55 |
| ▸ | GCGR | P47871 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2664047 | 0.92 | ADCYAP1R1 (0.72) | ADCYAP1R1NPC1RAB9ASPHK2SPHK1 | |
| SCHEMBL2664459 | 0.89 | ADCYAP1R1 (0.55) | ADCYAP1R1SPHK2SPHK1GCGR | |
| SCHEMBL2664199 | 0.85 | ADCYAP1R1 (0.62) | ADCYAP1R1SPHK2SPHK1GCGR | |
| SCHEMBL2664458 | 0.85 | GCGR (0.58) | ADCYAP1R1NPC1RAB9ASPHK2SPHK1 | |
| SCHEMBL2664188 | 0.85 | GCGR (0.70) | ADCYAP1R1GCGR | |
| SCHEMBL9072264 | 0.84 | ADCYAP1R1 (0.55) | ADCYAP1R1NPC1RAB9ASPHK2SPHK1 | |
| SCHEMBL2664333 | 0.83 | GCGR (0.56) | ADCYAP1R1NPC1RAB9ASPHK2SPHK1 | |
| SCHEMBL2664364 | 0.82 | ADCYAP1R1 (0.60) | ADCYAP1R1NPC1RAB9ASPHK2SPHK1 | |
| SCHEMBL2664645 | 0.82 | ADCYAP1R1 (0.61) | ADCYAP1R1GCGR | |
| SCHEMBL2664426 | 0.81 | ADCYAP1R1 (0.56) | ADCYAP1R1NPC1RAB9AGCGRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |