SCHEMBL2664196

SCHEMBL2664196

O=C(N/N=C/c1ccc(/C=C/CO)cc1)c1ccc(O)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADCYAP1R1 P41586 7/20 0.61
GCGR P47871 10/20 0.57
ESRRG P62508 1/20 0.51
DNM1 Q05193 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2664201 0.91 ADCYAP1R1 (0.59) ADCYAP1R1GCGRESRRGDNM1
SCHEMBL2664458 0.90 GCGR (0.58) ADCYAP1R1GCGRDNM1
SCHEMBL9072415 0.89 ADCYAP1R1 (0.60) ADCYAP1R1GCGRESRRGDNM1
SCHEMBL9072402 0.86 ADCYAP1R1 (0.61) ADCYAP1R1GCGRESRRG
SCHEMBL2664046 0.85 ADCYAP1R1 (0.55) ADCYAP1R1GCGRESRRG
SCHEMBL2664663 0.84 GCGR (0.55) ADCYAP1R1GCGRESRRG
SCHEMBL2664472 0.84 ADCYAP1R1 (0.56) ADCYAP1R1GCGRESRRG
SCHEMBL2664047 0.83 ADCYAP1R1 (0.72) ADCYAP1R1GCGR
SCHEMBL2664645 0.83 ADCYAP1R1 (0.61) ADCYAP1R1GCGR
SCHEMBL9072176 0.82 ADCYAP1R1 (0.65) ADCYAP1R1GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999001423-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 1999-01-14 WO disclosed