SCHEMBL26642736

SCHEMBL26642736

C=CCOCC(O)COP(=O)(O)OCC(N)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 16/20 0.56
GPR174 Q9BXC1 10/20 0.51
GPR34 Q9UPC5 7/20 0.51
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23130705 0.84 P2RY10 (0.45) P2RY10GPR174GPR34
Dexfosfoserine SCHEMBL28247522 0.84 P2RY10 (0.41) P2RY10GPR174GPR34CA1CA2
SCHEMBL8957176 0.80 P2RY10 (0.41) P2RY10GPR174GPR34
SCHEMBL8935176 0.79 P2RY10 (0.41) P2RY10GPR174GPR34CA1CA2
SCHEMBL457154 0.78 GRIK1 (0.46) CA1CA2CA7
SCHEMBL865368 0.78 GRIK1 (0.46) CA1CA2CA7
SCHEMBL13618513 0.78 P2RY10 (0.60) P2RY10GPR174GPR34
SCHEMBL13863415 0.77 P2RY10 (0.56) P2RY10GPR174GPR34
SCHEMBL22219423 0.77 P2RY10 (0.56) P2RY10GPR174GPR34
SCHEMBL21067706 0.77 P2RY10 (0.56) P2RY10GPR174GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023220387-A2 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed