SCHEMBL2664301

SCHEMBL2664301

COc1cc(C(=O)N/N=C/c2ccc(O)c3ccccc23)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GCGR P47871 16/20 1.00
MEN1 O00255 1/20 0.63
POLB P06746 1/20 0.63
GAA P10253 1/20 0.63
KMT2A Q03164 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9071998 0.94 GCGR (1.00) GCGRMEN1POLBGAAKMT2A
SCHEMBL9072324 0.89 GCGR (1.00) GCGRMEN1POLBGAAKMT2A
SCHEMBL2663998 0.89 GCGR (1.00) GCGRMEN1POLBGAAKMT2A
SCHEMBL9072064 0.88 GCGR (0.79) GCGRMEN1POLBGAAKMT2A
SCHEMBL2663638 0.87 GCGR (1.00) GCGRMEN1POLBGAAKMT2A
SCHEMBL12387716 0.87 GCGR (0.77) GCGRMEN1POLBGAAKMT2A
SCHEMBL24185041 0.86 GCGR (0.75) GCGRMEN1KMT2A
SCHEMBL32675182 0.86 GCGR (0.75) GCGRMEN1KMT2A
SCHEMBL2663737 0.85 GCGR (1.00) GCGRMEN1POLBGAAKMT2A
SCHEMBL2663970 0.84 GCGR (1.00) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999001423-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 1999-01-14 WO disclosed