Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL30644059 | 0.85 | ECE1 (0.36) | ECE1KDM4EALDH1A1SMPD3TUBB4A | |
| SCHEMBL26643172 | 0.84 | ECE1 (0.41) | ECE1ALDH1A1SMPD3KMT2ATUBB4A | |
| SCHEMBL26769899 | 0.77 | CHRM4 (0.40) | KDM4EPDPK1SMPD3RECQL | |
| SCHEMBL30775033 | 0.76 | CSNK2A1 (0.45) | ECE1ALDH1A1CSNK2A1TUBB4ATUBB | |
| SCHEMBL16277587 | 0.76 | CSNK2A1 (0.45) | ECE1ALDH1A1CSNK2A1TUBB4ATUBB | |
| SCHEMBL29912244 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL16114807 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL17793760 | 0.73 | KDM4E (0.65) | ECE1KDM4ECYP1A2ALDH1A1PDPK1 | |
| SCHEMBL25544916 | 0.73 | PIK3C3 (0.44) | ECE1KDM4EPDPK1SMPD3KMT2A | |
| SCHEMBL7939469 | 0.70 | HCRTR2 (0.58) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218023-A1 | THIAZOLOARYL-METHYL SUBSTITUTED CYCLIC HYDRAZINE-N-CARBOXAMIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-11-16 | — | — | WO | disclosed |