Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.46 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26643229 | 1.00 | HTR2A (0.55) | HTR2AKCNH2HTR2CTNFRSF1AP4HTM | |
| SCHEMBL31516476 | 1.00 | HTR2A (0.55) | HTR2AKCNH2HTR2CTNFRSF1AP4HTM | |
| SCHEMBL4318324 | 0.90 | HTR2A (0.51) | HTR2AKCNH2HTR2CTNFRSF1ABCL2L1 | |
| SCHEMBL4318319 | 0.90 | HTR2A (0.51) | HTR2AKCNH2HTR2CTNFRSF1ABCL2L1 | |
| SCHEMBL11472328 | 0.85 | MEN1 (0.52) | P4HTMP4HA1PIM1KDM4EMEN1 | |
| SCHEMBL11472332 | 0.85 | MEN1 (0.52) | P4HTMP4HA1PIM1KDM4EMEN1 | |
| SCHEMBL28619676 | 0.82 | BCL2L1 (0.65) | TNFRSF1ABCL2L1BADKMT2AHSD11B1 | |
| SCHEMBL26643204 | 0.82 | KMT2A (0.52) | HTR2AKCNH2HTR2CTNFRSF1AKDM4E | |
| SCHEMBL30644141 | 0.82 | KMT2A (0.52) | HTR2AKCNH2HTR2CTNFRSF1AKDM4E | |
| SCHEMBL2400178 | 0.80 | MAPT (0.64) | TNFRSF1AKDM4EMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313546-A1 | NUCLEIC ACID BINDERS | UNIVERSITY OF STRATHCLYDE (GB) | 2025-10-09 | — | — | US | disclosed |
| EP-4522588-A1 | NUCLEIC ACID BINDERS | University of Strathclyde (GB) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023218194-A1 | NUCLEIC ACID BINDERS | UNIVERSITY OF STRATHCLYDE (GB) | 2023-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313546-A1 | NUCLEIC ACID BINDERS | ZFR, NSUN3, POLI | HTR2A 4765/4885KCNH2 4674/4885HTR2C 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.