SCHEMBL26643295

SCHEMBL26643295

Cn1cc([N+](=O)[O-])cc1C(=O)NCCC#N

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
POLB P06746 2/20 0.36
RECQL P46063 1/20 0.36
AR P10275 4/20 0.36
HRAS P01112 1/20 0.36
ESR1 P03372 1/20 0.36
TOP1 P11387 1/20 0.36
ESR2 Q92731 1/20 0.36
KMT2A Q03164 3/20 0.36
PKM P14618 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HIF1A Q16665 1/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6257041 0.92 HRAS (0.47) MAPTPOLBARHRASESR1
SCHEMBL30644155 0.92 HRAS (0.47) MAPTPOLBARHRASESR1
SCHEMBL7506794 0.88 MAPT (0.36) MAPTPOLBHRASESR1TOP1
SCHEMBL7507389 0.88 MAPT (0.36) MAPTPOLBHRASESR1TOP1
SCHEMBL14441803 0.85 POLB (0.45) MAPTPOLBARKMT2APKM
SCHEMBL30644202 0.85 HRAS (0.45) MAPTPOLBARHRASESR1
SCHEMBL30644206 0.84 HRAS (0.45) MAPTPOLBARHRASESR1
SCHEMBL26374397 0.82 POLB (0.43) MAPTPOLBARKMT2APKM
SCHEMBL30644147 0.81 TOP1 (0.45) MAPTPOLBARHRASESR1
SCHEMBL4858229 0.79 TOP1 (0.41) MAPTPOLBHRASESR1TOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313546-A1 NUCLEIC ACID BINDERS UNIVERSITY OF STRATHCLYDE (GB) 2025-10-09 US disclosed
EP-4522588-A1 NUCLEIC ACID BINDERS University of Strathclyde (GB) 2025-03-19 EP disclosed
CN-119585239-A Nucleic acid binding agents 斯特拉斯克莱德大学 2025-03-07 CN disclosed
WO-2023218194-A1 NUCLEIC ACID BINDERS UNIVERSITY OF STRATHCLYDE (GB) 2023-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313546-A1 NUCLEIC ACID BINDERS ZFR, NSUN3, POLI MAPT 2605/4885POLB 95/4885RECQL 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.