SCHEMBL2664375

SCHEMBL2664375

O=C(N/N=C/c1ccc(OCCNCc2ccc(Cl)c(Cl)c2)c2ccccc12)c1ccc(O)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2664366 0.94 GCGR (0.89) GCGR
SCHEMBL2663927 0.93 GCGR (0.86) GCGR
SCHEMBL2664370 0.93 GCGR (0.86) GCGR
SCHEMBL2664369 0.92 GCGR (0.85) GCGR
SCHEMBL2664661 0.91 GCGR (0.84) GCGR
SCHEMBL2663955 0.91 GCGR (0.84) GCGR
SCHEMBL9072112 0.90 GCGR (0.82) GCGR
SCHEMBL9072205 0.89 GCGR (0.81) GCGR
SCHEMBL2664367 0.89 GCGR (0.83) GCGR
SCHEMBL2663933 0.89 GCGR (0.80) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999001423-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 1999-01-14 WO disclosed