SCHEMBL26644

SCHEMBL26644

[NH]c1nnn[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5838655 0.62
SCHEMBL8424100 0.62
Ammonia Solution, Strong SCHEMBL238233 0.62
SCHEMBL4870821 0.60
Ammonia Solution, Strong SCHEMBL6110378 0.58
SCHEMBL19387727 0.58
SCHEMBL1239469 0.58
Hydrochloric Acid SCHEMBL1487658 0.58
SCHEMBL266223 0.56
SCHEMBL6905309 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3395816-A1 ETHERS, SECONDARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2018-10-31 EP claimed
US-9221755-B2 Ethers, secondary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2015-12-29 US claimed
US-20140163032-A1 ETHERS, SECONDARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT 2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2014-06-12 US claimed
US-8680119-B2 Ethers, secondary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2014-03-25 US claimed
US-20120295938-A1 ETHERS, SECONDARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. 2012-11-22 US claimed
EP-1255797-B1 METHOD FOR ROUGHENING COPPER SURFACES FOR BONDING TO SUBSTRATES OMG ELECTRONIC CHEMICALS INC (US) 2012-06-13 EP claimed
US-20090186895-A1 ETHERS, SECONDARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2009-07-23 US claimed
EP-1613569-A4 SUBSTITUTED BASIC METAL NITRATES IN GAS GENERATION AUTOLIV ASP INC (US) 2009-06-03 EP claimed
EP-2027119-A2 ETHERS, SECONDARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2009-02-25 EP claimed
US-20080214660-A1 Compounds and Methods for the Inhibition of the Expression of VCAM-1 CRABTREE ACQUISITION CO, LLC 2008-09-04 US claimed
US-4861784-A Use of oxoquinazoline derivatives in the treatment of hyperuricaemia BOEHRINGER INGELHEIM KG (DE) 1989-08-29 US claimed
US-4847251-A CARDIOVASCULAR DISORDERS BOEHRINGER MANNHEIM GMBH (DE) 1989-07-11 US claimed
EP-0255704-A2 Pyridazinone derivatives, process for their preparation and their use as medicines Roche Diagnostics GmbH (DE) 1988-02-10 EP claimed
EP-0086723-B1 SUBSTITUTED PYRIMIDONES AND THEIR SALTS, THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS, COMPOSITIONS CONTAINING THEM AND INTERMEDIATES OBTAINED ROUSSEL-UCLAF (FR) 1987-04-22 EP claimed
US-4558046-A ANTIALLERGENS FARMITALIA CARLO ERBA, S.P.A. (IT) 1985-12-10 US claimed
US-4510143-A ANTIALLERGENS ROUSSEL UCLAF (FR) 1985-04-09 US claimed
EP-0086723-A2 Substituted pyrimidones and their salts, their preparation, their application as medicaments, compositions containing them and intermediates obtained ROUSSEL-UCLAF (FR) 1983-08-24 EP claimed
US-4248868-A FOR TREATING SYSTEMIC INFECTIONS BY GRAMPOSITIVE AND GRAM NEGATIVE BACTERIA CIBA-GEIGY CORPORATION (US) 1981-02-03 US claimed
US-4241068-A ANTIALLERGENS BOEHRINGER INGELHEIM GMBH (DE) 1980-12-23 US claimed
US-4083980-A ANTIALLERGENS BOEHRINGER INGELHEIM GMBH (DT) 1978-04-11 US claimed