Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCYAP1R1 | P41586 | 5/20 | 0.55 |
| ▸ | GCGR | P47871 | 11/20 | 0.54 |
| ▸ | ESRRG | P62508 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2664167 | 0.86 | ADCYAP1R1 (0.60) | ADCYAP1R1GCGRESRRGKMT2AMEN1 | |
| SCHEMBL2664434 | 0.85 | ADCYAP1R1 (0.59) | ADCYAP1R1GCGRESRRG | |
| SCHEMBL2664449 | 0.84 | ADCYAP1R1 (0.58) | ADCYAP1R1GCGRESRRG | |
| SCHEMBL2664447 | 0.83 | GCGR (0.55) | ADCYAP1R1GCGRESRRG | |
| SCHEMBL2664444 | 0.82 | ADCYAP1R1 (0.61) | ADCYAP1R1GCGRESRRGKDM4EALDH1A1 | |
| SCHEMBL9072136 | 0.82 | ADCYAP1R1 (0.59) | ADCYAP1R1GCGRESRRGMAPT | |
| SCHEMBL9072139 | 0.82 | ADCYAP1R1 (0.70) | ADCYAP1R1GCGRMAPTKMT2AMEN1 | |
| SCHEMBL9072137 | 0.82 | GCGR (0.60) | ADCYAP1R1GCGRESRRGMAPT | |
| SCHEMBL2664046 | 0.81 | ADCYAP1R1 (0.55) | ADCYAP1R1GCGRESRRGKDM4EALDH1A1 | |
| SCHEMBL9072405 | 0.80 | ADCYAP1R1 (0.61) | ADCYAP1R1GCGRESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |