Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 3/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 14/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | MST1 | P26927 | 1/20 | 0.37 |
| ▸ | STK4 | Q13043 | 1/20 | 0.37 |
| ▸ | STK3 | Q13188 | 1/20 | 0.37 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622341 | 1.00 | CSNK1D (0.46) | CSNK1DCSNK1EJAK3LIMK1LIMK2 | |
| SCHEMBL26644935 | 0.92 | JAK3 (0.43) | CSNK1DCSNK1EJAK3LIMK1LIMK2 | |
| SCHEMBL30622399 | 0.92 | JAK3 (0.43) | CSNK1DCSNK1EJAK3LIMK1LIMK2 | |
| SCHEMBL26644961 | 0.89 | JAK3 (0.44) | CSNK1DCSNK1EJAK3LIMK1LIMK2 | |
| SCHEMBL30622307 | 0.89 | JAK3 (0.44) | CSNK1DCSNK1EJAK3LIMK1LIMK2 | |
| SCHEMBL26645260 | 0.87 | CSNK1E (0.48) | CSNK1DCSNK1ELIMK1LIMK2LRRK2 | |
| SCHEMBL30623143 | 0.87 | CSNK1E (0.48) | CSNK1DCSNK1ELIMK1LIMK2LRRK2 | |
| SCHEMBL30622447 | 0.87 | JAK3 (0.42) | JAK3LIMK2LRRK2STK3STK26 | |
| SCHEMBL30622443 | 0.87 | JAK3 (0.42) | JAK3LIMK2LRRK2STK3STK26 | |
| SCHEMBL26644903 | 0.87 | JAK3 (0.42) | JAK3LIMK2LRRK2STK3STK26 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | claimed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |