Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 10/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.46 |
| ▸ | JAK3 | P52333 | 3/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622339 | 1.00 | CSNK1E (0.46) | CSNK1ECSNK1DJAK3ITKEGFR | |
| SCHEMBL30622385 | 0.92 | JAK3 (0.43) | CSNK1ECSNK1DJAK3ITKEGFR | |
| SCHEMBL26644879 | 0.92 | JAK3 (0.43) | CSNK1ECSNK1DJAK3ITKEGFR | |
| SCHEMBL30622307 | 0.89 | JAK3 (0.44) | CSNK1ECSNK1DJAK3EGFRLIMK1 | |
| SCHEMBL26644961 | 0.89 | JAK3 (0.44) | CSNK1ECSNK1DJAK3EGFRLIMK1 | |
| SCHEMBL30622404 | 0.89 | JAK3 (0.41) | CSNK1ECSNK1DJAK3LIMK1LIMK2 | |
| SCHEMBL26644850 | 0.89 | JAK3 (0.41) | CSNK1ECSNK1DJAK3LIMK1LIMK2 | |
| SCHEMBL30622939 | 0.89 | EGFR (0.45) | CSNK1ECSNK1DJAK3ITKEGFR | |
| SCHEMBL26645202 | 0.89 | EGFR (0.45) | CSNK1ECSNK1DJAK3ITKEGFR | |
| SCHEMBL30622996 | 0.87 | CSNK1E (0.45) | CSNK1ECSNK1DLIMK1LIMK2KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | claimed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |