Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.40 |
| ▸ | CPS1 | P31327 | 7/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 4/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622363 | 1.00 | EGFR (0.40) | EGFRCPS1KRASBTKROCK2 | |
| SCHEMBL26645448 | 0.90 | CPS1 (0.42) | CPS1ROCK2PRKG1 | |
| SCHEMBL26645077 | 0.88 | EGFR (0.38) | EGFRKRAS | |
| SCHEMBL26644933 | 0.88 | EGFR (0.38) | EGFRKRAS | |
| SCHEMBL26644898 | 0.88 | EGFR (0.38) | EGFRKRAS | |
| SCHEMBL30623091 | 0.87 | BTK (0.41) | EGFRBTK | |
| SCHEMBL26645414 | 0.87 | BTK (0.41) | EGFRBTK | |
| SCHEMBL26645415 | 0.87 | CYP11B1 (0.37) | EGFRKRAS | |
| SCHEMBL26645488 | 0.87 | CYP11B1 (0.37) | EGFRKRAS | |
| SCHEMBL26644890 | 0.87 | CYP11B1 (0.37) | EGFRKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |