Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 3/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | CCNK | O75909 | 3/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622344 | 1.00 | MAPK14 (0.42) | MAPK14CSNK1DMAPK11JAK3AURKB | |
| SCHEMBL26645464 | 1.00 | MAPK14 (0.42) | MAPK14CSNK1DMAPK11JAK3AURKB | |
| SCHEMBL30622306 | 1.00 | MAPK14 (0.42) | MAPK14CSNK1DMAPK11JAK3AURKB | |
| SCHEMBL26645356 | 0.92 | BRAF (0.38) | MAPK14CSNK1DMAPK11JAK3AURKB | |
| SCHEMBL26644942 | 0.92 | BRAF (0.38) | MAPK14CSNK1DMAPK11JAK3AURKB | |
| SCHEMBL30623112 | 0.92 | BRAF (0.38) | MAPK14CSNK1DMAPK11JAK3AURKB | |
| SCHEMBL26644847 | 0.87 | BTK (0.35) | JAK3EGFRCCNKCDK12BTK | |
| SCHEMBL30622348 | 0.87 | BTK (0.35) | JAK3EGFRCCNKCDK12BTK | |
| SCHEMBL30622366 | 0.87 | MAPK14 (0.46) | MAPK14CSNK1DMAPK11JAK3AURKB | |
| SCHEMBL26645123 | 0.87 | MAPK14 (0.46) | MAPK14CSNK1DMAPK11JAK3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |