Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16700558 | 0.82 | PDCD1 (0.52) | PDCD1CD274HTR2AHTR2CHTR2B | |
| SCHEMBL26645109 | 0.81 | PDCD1 (0.47) | PDCD1CD274HTR2AHTR2CNPC1 | |
| SCHEMBL30623111 | 0.81 | PDCD1 (0.47) | PDCD1CD274HTR2AHTR2CNPC1 | |
| SCHEMBL26645467 | 0.79 | PDCD1 (0.47) | PDCD1CD274KMOHTR2AHTR2C | |
| SCHEMBL30622782 | 0.79 | PDCD1 (0.47) | PDCD1CD274KMOHTR2AHTR2C | |
| SCHEMBL16699354 | 0.78 | PDCD1 (0.58) | PDCD1CD274HTR2AHTR2CLMNA | |
| SCHEMBL24276975 | 0.77 | PDCD1 (0.53) | PDCD1CD274JAK2JAK1TYK2 | |
| SCHEMBL26645268 | 0.76 | PDCD1 (0.50) | PDCD1CD274KMOEGLN2HTR2A | |
| SCHEMBL26645648 | 0.76 | PDCD1 (0.49) | PDCD1CD274HTR2AHTR2CHTR2B | |
| SCHEMBL26645568 | 0.75 | CDC7 (0.61) | KMOEGLN2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |