Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.36 |
| ▸ | SMO | Q99835 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26644890 | 0.90 | CYP11B1 (0.37) | CYP11B1CYP11B2SMOHDAC1HDAC2 | |
| SCHEMBL26645488 | 0.90 | CYP11B1 (0.37) | CYP11B1CYP11B2SMOHDAC1HDAC2 | |
| SCHEMBL26645415 | 0.90 | CYP11B1 (0.37) | CYP11B1CYP11B2SMOHDAC1HDAC2 | |
| SCHEMBL30622778 | 0.89 | NR1H2 (0.37) | APPCYP11B1CYP11B2HDAC1HDAC2 | |
| SCHEMBL26645433 | 0.87 | BCHE (0.39) | GHSRAKR1C3AKR1C2 | |
| SCHEMBL26645160 | 0.87 | BCHE (0.39) | GHSRAKR1C3AKR1C2 | |
| SCHEMBL26645193 | 0.87 | BCHE (0.39) | GHSRAKR1C3AKR1C2 | |
| SCHEMBL26645448 | 0.86 | CPS1 (0.42) | GHSR | |
| Hydrochloric Acid SCHEMBL26645153 | 0.78 | MAPK14 (0.35) | CYP11B1CYP11B2GRM2MAPK11MAPK14 | |
| Hydrochloric Acid SCHEMBL26645187 | 0.78 | MAPK14 (0.35) | CYP11B1CYP11B2GRM2MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |