Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379742 | 0.85 | KMT2A (0.53) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL295762 | 0.85 | KMT2A (0.53) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5379214 | 0.85 | KMT2A (0.53) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5379789 | 0.85 | KMT2A (0.53) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5385064 | 0.85 | KMT2A (0.53) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL23532889 | 0.85 | KMT2A (0.42) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL23533055 | 0.85 | KMT2A (0.42) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL23533054 | 0.85 | KMT2A (0.42) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29245127 | 0.85 | KMT2A (0.42) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL23532892 | 0.85 | KMT2A (0.42) | KMT2ACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4038060-B1 | DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR | PFIZER (US) | 2023-11-15 | — | — | EP | disclosed |