Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 20/20 | 1.00 |
| ▸ | MERTK | Q12866 | 20/20 | 1.00 |
| ▸ | MET | P08581 | 17/20 | 1.00 |
| ▸ | TYRO3 | Q06418 | 19/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21785667 | 1.00 | AXL (1.00) | AXLMERTKMETTYRO3 | |
| SCHEMBL30208879 | 1.00 | AXL (1.00) | AXLMERTKMETTYRO3 | |
| SCHEMBL21785506 | 0.92 | AXL (1.00) | AXLMERTKMETTYRO3 | |
| SCHEMBL30208999 | 0.92 | AXL (1.00) | AXLMERTKMETTYRO3 | |
| SCHEMBL21785501 | 0.92 | AXL (1.00) | AXLMERTKMETTYRO3 | |
| SCHEMBL21797873 | 0.92 | AXL (1.00) | AXLMERTKMETTYRO3 | |
| SCHEMBL30208968 | 0.92 | AXL (1.00) | AXLMERTKMETTYRO3 | |
| SCHEMBL21785978 | 0.91 | AXL (1.00) | AXLMERTKMETTYRO3 | |
| SCHEMBL21797881 | 0.91 | AXL (1.00) | AXLMERTKMETTYRO3 | |
| SCHEMBL21785640 | 0.91 | AXL (1.00) | AXLMERTKMETTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3843850-B1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES | ARRAY BIOPHARMA INC (US) | 2023-11-15 | — | — | EP | claimed |
| EP-3843850-B1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES | ARRAY BIOPHARMA INC (US) | 2023-11-15 | — | — | EP | disclosed |